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Article

Cartilage microRNA dysregulation in mouse osteoarthritis overlaps with patient disease candidates

2017-03-03

Abstract excerpt

<h4>ABSTRACT</h4> To explore the role of microRNAs in osteoarthritis (OA), we conducted microRNA expression profiling on micro-dissected tibial cartilage and subchondral bone in a mouse model of OA produced by medial meniscus destabilization (DMM). DMM mice had characteristic cartilage degeneration, subchondral bone sclerosis and osteophyte formation. While subchondral bone showed no microRNA dysregulation, 139 m...

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Literature Corpus work
b650f919-54a2-54ac-8394-f142a587fa2e
DOI
10.1101/113456
Open publication

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Cartilage microRNA dysregulation in mouse osteoarthritis overlaps with patient disease candidatesDOI 10.1101/113456
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