Article
Systematic Identification, Characterization and Target Gene Analysis of microRNAs Involved in Osteoarthritis Subchondral Bone Pathogenesis.
Calcified tissue international - 1 Jul 2016
Prasadam Indira, Batra Jyotsna, Perry Samuel, Gu Wenyi, Crawford Ross, Xiao Yin
Abstract excerpt
This study aimed to identify the microRNAs associated with sclerotic status of subchondral bone in the pathogenesis of osteoarthritis (OA). Total RNA was extracted from non-sclerotic and sclerotic OA subchondral bone from patients undergoing knee replacement surgeries. miRCURY™ LNA miRNA chip and...
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