Article
Variant Discovery and Fine Mapping of Genetic Loci Associated with Blood Pressure Traits in Hispanics and African Americans.
PloS one - 1 Jan 2016
Franceschini Nora, Carty Cara L, Lu Yingchang, Tao Ran, Sung Yun Ju, Manichaikul Ani, Haessler Jeff, Fornage Myriam, Schwander Karen, Zubair Niha, Bien Stephanie, Hindorff Lucia A, Guo Xiuqing, Bielinski Suzette J, Ehret Georg, Kaufman Joel D, Rich Stephen S, Carlson Christopher S, Bottinger Erwin P, North Kari E, Rao D C, Chakravarti Aravinda, Barrett Paula Q, Loos Ruth J F, Buyske Steven, Kooperberg Charles
Abstract excerpt
Despite the substantial burden of hypertension in US minority populations, few genetic studies of blood pressure have been conducted in Hispanics and African Americans, and it is unclear whether many of the established loci identified in European-descent populations contribute to blood pressure variation in non-European descent populations. Using the Metabochip array, we sought to characterize the genetic...
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