Article

Bi-directional relationship between the biofilm of <i>Porphyromonas gingivalis</i> and the amyloid-beta peptide

2025-05-17

Abstract excerpt

Periodontitis and Porphyromonas gingivalis infections are significant risk factors for the onset of Alzheimer’s disease (AD). Despite P. gingivalis relying on biofilm for its survival and virulence, the impact of the extracellular matrix on AD’s neuropathological hallmarks was never examined. In this study, we report a bidirectional relationship between the amyloid beta (Aβ) peptide, which plays a central role i...

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Literature Corpus work: b5f4fe6e-080f-50d1-9339-226824607aa4
DOI: 10.1101/2025.05.16.654480

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