Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interaction between genetic factors, Porphyromonas gingivalis and microglia to promote Alzheimer’s disease

1 Jan 2020

Abstract excerpt

In late-onset Alzheimer disease (AD) pathogenesis, genes, infections and immunity could be significant factors. We have reviewed if the keystone periodontal pathogen Porphyromonas gingivalis may affect genes and microglia (primary immune cells in the brain) to promote AD development. Genes for apolipoprotein, clusterin, CD33, triggering receptor expressed on myeloid cells-2 (TREM-2), tyrosine kinase binding...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Neuroinflammation and Neurodegeneration Mechanisms
Share to S100 Proteins and Annexins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33062201
DOI: 10.1080/20002297.2020.1820834

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interaction between genetic factors, Porphyromonas gingivalis and microglia to promote Alzheimer’s diseasePMID 33062201Read ↗

Exploring the Connection between Porphyromonas gingivalis and Neurodegenerative Diseases: A Pilot Quantitative Study on the Bacterium Abundance in Oral Cavity and the Amount of Antibodies in SerumSemantic proximity Read ↗

Porphyromonas gingivalis and the pathogenesis of Alzheimer’s diseaseSemantic proximity Read ↗

The role of the oral microbiome, host response, and periodontal disease treatment in Alzheimer's disease: A primerSemantic proximity Read ↗

Is there a link between genetic defects in the complement cascade andPorphyromonas gingivalisin Alzheimer’s disease?Semantic proximity Read ↗

Porphyromonas gingivalis Outer Membrane Vesicles as the Major Driver of and Explanation for Neuropathogenesis, the Cholinergic Hypothesis, Iron Dyshomeostasis, and Salivary Lactoferrin in Alzheimer’s DiseaseSemantic proximity Read ↗

Can oral infection be a risk factor for Alzheimer's disease?Semantic proximity Read ↗

The role of microbiome-host interactions in the development of Alzheimer´s diseaseSemantic proximity Read ↗

The role of inflammation and genetics in periodontal diseaseSemantic proximity Read ↗

Genetic, Transcriptome, Proteomic, and Epidemiological Evidence for Blood-Brain Barrier Disruption and Polymicrobial Brain Invasion as Determinant Factors in Alzheimer’s DiseaseSemantic proximity Read ↗

Porphyromonas gingivalis: An Overview of Periodontopathic Pathogen below the Gum LineSemantic proximity Read ↗

Association of perturbation of oral bacterial with incident of Alzheimer's disease: A pilot studySemantic proximity Read ↗

Late onset Alzheimer's disease genetics implicates microglial pathways in disease risk.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.