Article

SLC6A14 impacts cystic fibrosis lung disease severity via mTOR and epithelial repair modulation

2022-01-07

Abstract excerpt

<title>Abstract</title> <p>Cystic fibrosis (CF), due to variants in <italic>CFTR</italic> gene, is associated with chronic infection/inflammation responsible for airway epithelium alteration and lung function decline. Modifier genes induce phenotype variability between people with CF (pwCF) carrying the same <italic>CFTR</italic> variants. Among these, the gene encoding for the amino acid transporter SLC6A14 has...

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Literature Corpus work: b578e7a0-598b-5a9a-9958-90589eae5599
DOI: 10.21203/rs.3.rs-591564/v3

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