Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Update on SLC6A14 in lung and gastrointestinal physiology and physiopathology: focus on cystic fibrosis.

Cellular and molecular life sciences : CMLS - 1 Sept 2020

Ruffin Manon, Mercier Julia, Calmel Claire, Mésinèle Julie, Bigot Jeanne, Sutanto Erika N, Kicic Anthony, Corvol Harriet, Guillot Loic

Abstract excerpt

The solute carrier family 6 member 14 (SLC6A14) protein imports and concentrates all neutral amino acids as well as the two cationic acids lysine and arginine into the cytoplasm of different cell types. Primarily described as involved in several cancer and colonic diseases physiopathological mechanisms, the SLC6A14 gene has been more recently identified as a genetic modifier of cystic fibrosis (CF) disease...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Transport Systems
Share to Cystic Fibrosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gastrointestinal Tract

Share to Genetic Variation

Share to Linkage Disequilibrium

Share to Neoplasms

Share to Severity of Illness Index

Source

Open in PubMed Open full text

Identifiers

PMID: 32166393
DOI: 10.1007/s00018-020-03487-x
PMCID: PMC7426304

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Update on SLC6A14 in lung and gastrointestinal physiology and physiopathology: focus on cystic fibrosis.PMID 32166393Read ↗

SLC6A14, an amino acid transporter, modifies the primary CF defect in fluid secretionSemantic proximity Read ↗

Changing paradigms in the treatment of gastrointestinal complications of cystic fibrosis in the era of cystic fibrosis transmembrane conductance regulator modulators.Semantic proximity Read ↗

Cystic fibrosis.Semantic proximity Read ↗

Gastrointestinal pathophysiology and nutrition in cystic fibrosis.Semantic proximity Read ↗

[Cystic fibrosis--review].Semantic proximity Read ↗

Update on pathogenesis of cystic fibrosis lung diseaseSemantic proximity Read ↗

Potential Theranostic Roles of SLC4 Molecules in Human Diseases.Semantic proximity Read ↗

Multiple apical plasma membrane constituents are associated with susceptibility to meconium ileus in individuals with cystic fibrosis.Semantic proximity Read ↗

A bird eye view on cystic fibrosis: An underestimated multifaceted chronic disorder.Semantic proximity Read ↗

SLC6A14 Is a Genetic Modifier of Cystic Fibrosis That Regulates Pseudomonas aeruginosa Attachment to Human Bronchial Epithelial CellsSemantic proximity Read ↗

Intestinal dysbiosis and inflammation in cystic fibrosis impacts gut and multi-organ axesSemantic proximity Read ↗

SLC6A14 Impacts Cystic Fibrosis Lung Disease Severity via mTOR and Epithelial Repair ModulationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.