Article
A synthetic delivery vector for mucosal vaccination
2023-05-16
Abstract excerpt
The success of mRNA-based vaccines during the Covid-19 pandemic has highlighted the value of this new platform for vaccine development against infectious disease. However, the CD8 + T cell response remains modest with mRNA vaccines, and these do not induce mucosal immunity, which would be needed to prevent viral spread in the healthy population. To address this drawback, we developed a dendritic cell targeting mu...
Topics
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- Bacteriophages and microbial interactions
- Biochemical and Structural Characterization
- Immunotherapy and Immune Responses
- Microbial Inactivation Methods
- Monoclonal and Polyclonal Antibodies Research
- RNA Interference and Gene Delivery
- SARS-CoV-2 and COVID-19 Research
- vaccines and immunoinformatics approaches
Identifiers and source
- Literature Corpus work
- b544a4c1-5c3d-5ab8-837c-2719a6f5430e
- DOI
- 10.1101/2023.05.15.540756
