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Senescence protein signatures predict dementia risk with causal implication for TBCA: a two-cohort study

2026-03-26

Abstract excerpt

<title>Abstract</title> <p>Senescence, a key aging mechanism, is linked to disease via the senescence-associated secretory phenotype (SASP), yet its role in dementia remains unclear. We aimed to identify a minimal circulating SASP protein panel to predict incident dementia and identify causally-associated proteins. Among midlife and late-life participants from the Atherosclerosis Risk in Communities (ARIC) study,...

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Literature Corpus work
b50e259e-33de-5114-a277-089ffd8cf8f6
DOI
10.21203/rs.3.rs-9131525/v1
Open publication

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Senescence protein signatures predict dementia risk with causal implication for TBCA: a two-cohort studyDOI 10.21203/rs.3.rs-9131525/v1
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