Article

Early-life nutritional environment is associated with late-life cognition in the Health and Retirement Study, a pellagra epidemic natural experiment

2026-06-22

Abstract excerpt

<h4>ABSTRACT</h4> Early-life exposures are important to several late-life health outcomes. We sought to study the effect of an in utero nutritional environment and its interaction with Alzheimer’s disease (AD) genetic risk on late-life cognitive function. We used a natural experiment created by the pellagra epidemic, a nutritional disease caused by a vitamin B 3 deficiency, to evaluate the association between...

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Literature Corpus work: b4923b2b-d90f-5141-bcba-069d69cfd0a8
DOI: 10.64898/2026.06.11.26355481

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