Article

Validation of HER2 status in whole genome sequencing data of breast cancers with AI-driven, ploidy-corrected approach

2021-09-05

Abstract excerpt

The HER2 protein overexpression is one of the most significant biomarkers for breast cancer diagnostics, prediction, and prognostics. The availability of HER2-inhibitors in routine clinical practice directly translates into the diagnostic need for precise and robust marker identification. At the brink of the genomic era, multigene next-generation sequencing methodologies slowly take over the field of single-biomar...

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Literature Corpus work: b444026a-30e5-5dd6-b4d9-09322d466f4c
DOI: 10.1101/2021.08.30.21258379

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