Article

Nitrogen utilisation by the metabolic generalist pathogen <i>Mycobacterium tuberculosis</i>

2018-08-05

Abstract excerpt

Bacterial metabolism is fundamental to pathogenesis and has a dominant effect on bacterial killing by antibiotics. Here we explore how Mycobacterium tuberculosis utilises amino acids as nitrogen sources, using a combination of bacterial physiology and stable isotope tracing coupled to liquid chromatography mass spectrometry metabolomics methods. Our results define core properties of the nitrogen metabolic network...

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Literature Corpus work: b4282ecc-551f-5674-b78f-4d6d4fb47053
DOI: 10.1101/385278

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