Article
D-mannose ameliorates age-associated cellular senescence in the bladder urothelium and NLRP3/Gasdermin/IL-1β -driven pyroptotic epithelial cell shedding
2022-09-06
Abstract excerpt
<h4>ABSTRACT</h4> Aging is a risk factor for disease via increased susceptibility to infection, decreased ability to maintain homeostasis, inefficiency in combatting stress, and decreased regenerative capacity. Multiple diseases including urinary tract infection (UTI), are more prevalent with age; however, the mechanisms underlying how aging affects the urinary tract mucosa and the reason why aging correlates wit...
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Identifiers and source
- Literature Corpus work
- b3e8c534-84a7-57f8-a451-9c45a471bf18
- DOI
- 10.1101/2022.09.06.506836
