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D-mannose ameliorates age-associated cellular senescence in the bladder urothelium and NLRP3/Gasdermin/IL-1β -driven pyroptotic epithelial cell shedding

2022-09-06

Abstract excerpt

<h4>ABSTRACT</h4> Aging is a risk factor for disease via increased susceptibility to infection, decreased ability to maintain homeostasis, inefficiency in combatting stress, and decreased regenerative capacity. Multiple diseases including urinary tract infection (UTI), are more prevalent with age; however, the mechanisms underlying how aging affects the urinary tract mucosa and the reason why aging correlates wit...

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Literature Corpus work
b3e8c534-84a7-57f8-a451-9c45a471bf18
DOI
10.1101/2022.09.06.506836
Open publication

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D-mannose ameliorates age-associated cellular senescence in the bladder urothelium and NLRP3/Gasdermin/IL-1β -driven pyroptotic epithelial cell sheddingDOI 10.1101/2022.09.06.506836
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