Article

A 50-gene high-risk profile predictive of COVID-19 and Idiopathic Pulmonary Fibrosis mortality originates from a genomic imbalance in monocyte and T-cell subsets that reverses in survivors with post-COVID-19 Interstitial Lung Disease

2023-10-24

Abstract excerpt

<h4>Background</h4> We aim to study the source of circulating immune cells expressing a 50-gene signature predictive of COVID-19 and IPF mortality. <h4>Methods</h4> Whole blood and Peripheral Blood Mononuclear cells (PBMC) were obtained from 231 subjects with COVID-19, post-COVID-19-ILD, IPF and controls. We measured the 50-gene signature (nCounter, Nanostring), interleukin 6 (IL6), interferon γ-induced protein...

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Literature Corpus work: b38ff70c-c162-5c9a-9b2e-a0e66f84a5bc
DOI: 10.1101/2023.10.22.563156

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