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Mesenchymal Transition as a Potential Mechanism of Late Immune Evasion in Neuroblastoma: A Case of Late Relapse after Allogeneic Hematopoietic Stem Cell Transplantation

2026-04-09

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> Neuroblastoma is the most common extracranial solid malignant tumor in children, and recurrence is not uncommon in high-risk cases, with immune evasion considered a key mechanism underlying relapse and drug resistance. Neural crest progenitor cells differentiate into adrenergic or mesenchymal phenotypes. MES-type neuroblastoma exhibits greater resistance to th...

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Literature Corpus work: b3753f48-7e29-5d40-afe3-01ed623f3850
DOI: 10.21203/rs.3.rs-9280514/v1

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