Article

Design and validation of a multi-point injection technology for MR-guided convection enhanced delivery in the brain

2021-06-25

Abstract excerpt

Convection enhanced delivery (CED) allows direct intracranial administration of neuro-therapeutics. Success of CED relies on specific targeting and broad volume distributions (V D ). However, to prevent off-target delivery and tissue damage, CED is typically conducted with small cannulas and at low flow rates, which critically limit the maximum achievable V D . Furthermore, in applications such as gene therapy r...

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Literature Corpus work: b33936eb-9526-5302-8c4a-26e3fe00b187
DOI: 10.1101/2021.06.24.449788

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