Article
In vitro design of intrathecal drug administration therapies
2025-11-29
Abstract excerpt
1 Due to the scarcity of reliable in vivo data, the pharmacokinetics of intrathecally (IT) administered drugs remain inadequately quantified. Designing new therapies is further hindered by variability in experimental methods, inter-individual and inter-species differences, and poor reproducibility across animal and human studies. To address these limitations, we developed an anatomically accurate, subject-specific...
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Identifiers and source
- Literature Corpus work
- 9f91e707-3baa-5c00-971b-d5e6c853e652
- DOI
- 10.1101/2025.11.25.690590