Article

Omicron Spike confers enhanced infectivity and interferon resistance to SARS-CoV-2 in human nasal tissue

2023-05-08

Abstract excerpt

<h4>Summary</h4> Omicron emerged following COVID-19 vaccination campaigns, displaced previous SARS-CoV-2 variants of concern worldwide, and gave rise to lineages that continue to spread. Here, we show that Omicron exhibits increased infectivity in primary adult upper airway tissue relative to Delta. Using recombinant forms of SARS-CoV-2 and nasal epithelial cells cultured at the liquid-air interface, enhanced inf...

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Literature Corpus work: b2ccaa9f-eb2c-5d8b-8a79-0fe63ff0d163
DOI: 10.1101/2023.05.06.539698

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