Article

SARS-CoV-2 Omicron is specifically restricted in its replication in human lung tissue, compared to other variants of concern

2022-03-31

Abstract excerpt

<h4>ABSTRACT</h4> SARS-CoV-2 Omicron variant has been characterized by decreased clinical severity, raising the question of whether early variant-specific interactions within the mucosal surfaces of the respiratory tract could mediate its attenuated pathogenicity. Here, we employed ex vivo infection of native human nasal and lung tissues to investigate the local-mucosal susceptibility and innate immune response...

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Literature Corpus work: 6ae9b6cf-f320-5917-8155-b057911c9b36
DOI: 10.1101/2022.03.31.486531

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