Article

A novel short transcript isoform of chicken IRF7 negatively regulates interferon-β production

2022-12-31

Abstract excerpt

Type I interferon (IFN-I) provides an important first line to protect avian species against pathogens invasion. IFN regulatory factor 7 (IRF7) has been identified as the most important regulator for both DNA and RNA virus-induced IFN-I production in chickens. Although four splicing variants of IRF7 have been identified in mammals, it is still unclear whether alternative splicing patterns and the function of IRF7 i...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: b2a921fd-f1f3-57d9-957c-366b92be934d
DOI: 10.1016/j.jia.2022.12.015

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A novel short transcript isoform of chicken IRF7 negatively regulates interferon-β productionDOI 10.1016/j.jia.2022.12.015Read

Chicken interferon regulatory factor 7 (IRF7) can control ALV-J virus infection by triggering type I interferon production through affecting genes related with innate immune signaling pathwaySemantic proximity Read

Avian IRF1 and IRF7 Play Overlapping and Distinct Roles in Regulating IFN-Dependent and -Independent Antiviral Responses to Duck Tembusu Virus InfectionSemantic proximity Read

Chicken DDX1 Acts as an RNA Sensor to Mediate IFN-β Signaling Pathway Activation in Antiviral Innate ImmunitySemantic proximity Read

Interferon regulatory factor 7- (IRF7-) mediated immune response affects Newcastle disease virus replication in chicken embryo fibroblastsSemantic proximity Read

IRF7: role and regulation in immunity and autoimmunitySemantic proximity Read

Alternate isoforms of IRF7 Differentially Regulate Interferon Expression to Tune Response to Viral InfectionSemantic proximity Read

Tissue and time specific expression pattern of interferon regulated genes in the chickenSemantic proximity Read

Functions of the two zebrafish MAVS variants are opposite in the induction of IFN1 by targeting IRF7.Semantic proximity Read

Conserved Function of Bat IRF7 in Activating Antiviral Innate Immunity Insights into the Innate Immune Response in BatsSemantic proximity Read

Molecular cloning and characterization of interferon regulatory factor 7 (IRF-7) in Japanese flounder, Paralichthys olivaceusSemantic proximity Read

Determination of antiviral action of long non-coding RNA loc107051710 during infectious bursal disease virus infection due to enhancement of interferon productionSemantic proximity Read

Interferon Regulatory Factors IRF1 and IRF7 Directly Regulate Gene Expression in Bats in Response to Viral InfectionSemantic proximity Read