Morphometric analysis of the lens in human aniridia and mouse Small eye.

Abstract excerpt

Congenital aniridia is caused by heterozygous mutations in the PAX6 gene. In this disease, congenital iris and foveal hypoplasia is associated with juvenile onset cataract, glaucoma, and corneal keratopathy. In rodents, Pax6 mutations result in a congenital reduction in ocular size that is not typically described in human aniridia. Here, the ocular morphometry of aniridia patients is compared with the lens...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Aniridia
• Share to Cataract