Article

Enhanced eosinophilic inflammation associated with antibody and complement-mediated pneumonic insults in severe COVID-19

2020-11-03

Abstract excerpt

Despite the worldwide effect of the Coronavirus disease 2019 (COVID-19) pandemic, the underlying mechanisms of fatal viral pneumonia remain elusive. Here, we conducted kinetic profiling of respiratory leukocytes and associated inflammatory mediators to show that severe COVID-19 is associated with delayed but enhanced eosinophilic inflammation when compared to mild cases. In addition, we confirmed increased Th2-bia...

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Literature Corpus work: b23f6be5-da39-5be0-b3a6-27c774488f9d
DOI: 10.21203/rs.3.rs-101027/v1

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