Article
The CXCL10/CXCR3 axis is essential for sustaining immunological dormancy in breast cancer
2025-09-29
Abstract excerpt
Immune surveillance plays a pivotal role in controlling tumor emergence, dormancy and progression, including in breast cancer. Despite its potential clinical relevance, the mechanisms governing dormancy initiation, maintenance and escape, as well as the molecular mediators involved, remain poorly understood. Here, we identify the interferon-inducible chemokine CXCL10 and its receptor CXCR3 as key regulators of imm...
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Identifiers and source
- Literature Corpus work
- b22c7e76-820f-57c4-8e36-13f87e269830
- DOI
- 10.1101/2025.09.26.678769