Article

CerS6 gene methylation in peripheral blood is associated with asthma and the frequent exacerbator phenotype

2024-10-28

Abstract excerpt

<title>Abstract</title> <p>Background Sphingolipids metabolism regulated by ceramide synthase (<italic>CerS</italic>) enzyme is closely related to asthma development, but the underlying biological mechanism remains unclear. Given the critical role of epigenetics in the pathogenesis of asthma, we explored the DNA methylation patterns of <italic>CerS1-6</italic>, the genes encoding the <italic>CerS</italic> enzyme...

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Literature Corpus work: b22aa3c7-e48a-50b7-b9f9-4c3a1ce87fc6
DOI: 10.21203/rs.3.rs-5309554/v1

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