Article

Implications of SARS-CoV-2 mutations for genomic RNA structure and host microRNA targeting

2020-05-16

Abstract excerpt

The SARS-CoV-2 virus is a recently-emerged zoonotic pathogen already well adapted to transmission and replication in humans. Although the mutation rate is limited, recently introduced mutations in SARS-CoV-2 have the potential to alter viral fitness. In addition to amino acid changes, mutations could affect RNA secondary structure critical to viral life cycle, or interfere with sequences targeted by host miRNAs. W...

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Literature Corpus work: b1de7baa-b859-5543-a424-75028eb3b29a
DOI: 10.1101/2020.05.15.098947

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