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Article

MicroRNA-driven evolutionary pressure in SARS-CoV-2: the role of hsa-miR-6512 in mutational dynamics.

Scientific reports - 19 Nov 2025

Razban Pegah, Mehrmohamadi Mahya, Karimi Mahdi, Saadatpour Fatemeh, Arefian Ehsan

Abstract excerpt

The SARS-CoV-2 pandemic, first reported as an acute respiratory disease in December 2019 in Wuhan, China, has profoundly impacted global communities, with approximately seven million deaths reported by the World Health Organization to date. Coronaviruses exhibit a high recombination rate due to RNA-dependent RNA polymerase transcription errors, resulting in mutations that are selectively conserved under...

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Identifiers

PMID: 41258252
DOI: 10.1038/s41598-025-24578-4
PMCID: PMC12630704

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