Article

RNA genome conservation and secondary structure in SARS-CoV-2 and SARS-related viruses

2020-03-28

Abstract excerpt

As the COVID-19 outbreak spreads, there is a growing need for a compilation of conserved RNA genome regions in the SARS-CoV-2 virus along with their structural propensities to guide development of antivirals and diagnostics. Using sequence alignments spanning a range of betacoronaviruses, we rank genomic regions by RNA sequence conservation, identifying 79 regions of length at least 15 nucleotides as exactly conse...

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Literature Corpus work: d708dd2f-ca11-5f5f-8653-b9d69d970ab6
DOI: 10.1101/2020.03.27.012906

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