Article

Artificial Intelligence for Mapping Cellular and Neural Circuit State Transitions in Human Disease: Toward Multiscale Disease Modeling

2026-04-22

Abstract excerpt

Understanding human disease requires frameworks that can connect molecular and cellular perturbations to systems-level dysfunction and clinical phenotype across time. Recent advances in single-cell and spatial profiling have revealed that cellular identity is dynamic and distributed across continuous state landscapes, while developments in electrophysiology, neuroimaging, and circuit analysis have underscored the...

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Literature Corpus work: b1ca30ed-24e2-5f0b-9a4a-25daeb78d802
DOI: 10.20944/preprints202604.1579.v1

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