Article

Peroxisomal β-oxidation enzyme, DECR2, regulates lipid metabolism and promotes treatment resistance in advanced prostate cancer

2022-11-05

Abstract excerpt

<h4>ABSTRACT</h4> Peroxisomes are central metabolic organelles that have key roles in fatty acid homeostasis, including β-oxidation, and emerging evidence has linked aberrant peroxisome metabolism to cancer development and progression. While targeting mitochondrial β-oxidation in prostate cancer (PCa) has gained significant attention in recent years, the contribution of peroxisomal β-oxidation (perFAO) to PCa tum...

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Literature Corpus work: b1b414ae-62e8-5a65-8791-b1770522f043
DOI: 10.1101/2022.11.05.515262

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