Article

Towards universal modeling of transcript isoform expression levels

2025-07-25

Abstract excerpt

A holy grail in computational biology is accurate modeling of transcript expression levels using epigenetic features, which would provide a quantitative way to study gene regulation in normal and disease states. Previous studies relied heavily on immortalized cell lines that exhibit properties different from cells in natural tissue environments. Most studies also quantified the expression of each gene by a single...

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Literature Corpus work: b12ec054-5605-56d7-8ae9-6c968e642245
DOI: 10.1101/2025.07.21.665977

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