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Article

Genome-wide analysis of transcript isoform variation in humans.

Nature genetics - 1 Feb 2008

Kwan Tony, Benovoy David, Dias Christel, Gurd Scott, Provencher Cathy, Beaulieu Patrick, Hudson Thomas J, Sladek Rob, Majewski Jacek

Abstract excerpt

We have performed a genome-wide analysis of common genetic variation controlling differential expression of transcript isoforms in the CEU HapMap population using a comprehensive exon tiling microarray covering 17,897 genes. We detected 324 genes with significant associations between flanking SNPs and transcript levels. Of these, 39% reflected changes in whole gene expression and 55% reflected transcript isoform...

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PMID: 18193047
DOI: 10.1038/ng.2007.57

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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