Article

Flavivirus serocomplex cross-reactive immunity is protective by activating heterologous memory CD4 T cells

2019-01-30

Abstract excerpt

Purpose: How prior immunity influences immune memory recall and protection against related flaviviruses is largely unknown; yet encounter with multiple flaviviruses in a lifetime is increasingly likely. Here, we aimed to determine whether serocomplex cross-reactive immunity is detrimental during vaccination or if it can prime for protective immune responses.

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Identifiers and source

Literature Corpus work: b1207a71-5c51-5546-9755-cb5a16bf13a2
DOI: 10.1016/j.ijid.2018.11.048

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