Article

CircLMF1 Activates the TFE3-MVP/ABCC1 Pathway to Promote Mesenchymal Transition and Sensitize Glioblastoma to Ferroptosis

2026-08-13

Abstract excerpt

<title>Abstract</title> <p> <bold>Background:</bold> Proneural-mesenchymal transition (PMT), a glioblastoma (GBM)-specific process driving tumor progression, has not been linked to ferroptosis susceptibility in GBM. In contrast, invasive tumor cells exhibit ferroptosis sensitivity in carcinomas, highlighting the unexplored role of GBM-specific PMT in ferroptosis regulation. While circular RNAs (circRNAs) contri...

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Literature Corpus work: b0d956af-029c-5d9d-8557-4011b9ba6cbc
DOI: 10.21203/rs.3.rs-9394829/v1

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