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Circular RNA TFRC/SCD1 mRNA interaction regulates ferroptosis and metastasis in gastric cancer

5 Jun 2025

Abstract excerpt

Ferroptosis, an iron-dependent form of programmed cell death, holds promise for cancer treatment. Circular RNAs (circRNAs), widely expressed across tumor types, modulate multiple cellular biological processes, including ferroptosis. However, the regulatory dynamics of circRNAs in gastric cancer (GC)-associated ferroptosis remain poorly understood. Here, circTFRC (circBase ID: hsa_circ_0068606), a novel circRNA,...

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PMID: 40473597
DOI: 10.1038/s41419-025-07759-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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