Article

Single Nucleotide Mutation Changes the Capability of CCN3 in Osteosarcoma Cell Invasion and Differentiation

2022-03-29

Abstract excerpt

<h4>Background: </h4> This study is designed to identify the significant mutations in CCN3 gene in osteosarcoma and explore its influence in cell invasion and differentiation and the underlying mechanism. <h4>Methods: </h4>: Sanger sequencing was applied to identify CCN3 gene sequence in human osteosarcoma cell lines, peripheral blood mononuclear cells (PBMC) and osteosarcoma tissue. Wildtype and mutant CCN3 (mCCN...

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Literature Corpus work: b09999a5-e7d0-5fde-b9a7-adc4d76d9a1b
DOI: 10.21203/rs.3.rs-1487275/v1

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