Article

Artemis (DCLRE1C) Acts as a Target to Enhance Radiotherapy Response in Triple-Negative Breast Cancer

2025-03-27

Abstract excerpt

Lack of canonical biomarkers and strategies to target radioresistance contribute to poor patient outcomes in triple-negative breast cancer (TNBC). Identifying and targeting novel radioresistance genes will benefit in enhancing radiotherapy response and treatment outcome in TNBC patients. A genome-wide CRISPR screen was performed to identify radioresistance genes in the MDA-MB-231 TNBC cell line. An in vitro clonog...

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Literature Corpus work: b0822ba4-3865-599f-b555-cbeaa0bf3683
DOI: 10.20944/preprints202503.2109.v1

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