Article
An efficient, reproducible and accurate RT-qPCR based method to determine mumps specific neutralizing antibody.
Journal of virological methods - 1 Mar 2020
Sikazwe Chisha T, Levy Avram, Speers David, Smith David W
Abstract excerpt
INTRODUCTION: A resurgence of mumps among fully vaccinated adolescents and young adults globally has led to questions about the longevity of vaccine derived specific immunity. Unfortunately, the ideal serological correlate of immunity to mumps has yet to be identified. However, neutralising antibody titres in serum are used extensively as a surrogate marker of immunity to mumps. Conventional neutralisation tests...
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