Article

<i>Identification and Characterization of Rare Pathogenic</i> Gene <i>tic Variants Associated with Breast Cancer Susceptibility in 1000 Genome and gnomAD Population</i>

2025-09-02

Abstract excerpt

<h4>Background</h4> Inherited variants in cancer susceptibility genes play a critical role in breast cancer risk, yet comprehensive comparative analyses across clinically relevant genes remain limited. While BRCA1 and BRCA2 are well-established high-risk contributors, the broader landscape of germline pathogenicity across breast cancer associated genes warrants systematic evaluation. <h4>Methods</h4> We curat...

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Literature Corpus work: b02ef0b4-bc52-56a1-b299-878a3a1a7869
DOI: 10.1101/2025.08.30.25334747

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