Article

The Multi-System Roles of Dp71 Dystrophin Isoforms in Duchenne Muscular Dystrophy

2026-03-31

Abstract excerpt

The DMD gene is well known for its product dystrophin, a large rod-shaped protein that plays a critical role in muscular membrane strength and integrity. Mutations affecting dystrophin lead to Duchenne muscular dystrophy, a fatal X-linked disease characterized by muscular weakness and breakdown. In addition to the full-length dystrophin product that is most often associated with disease, the DMD gene also encodes...

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Literature Corpus work: b0059ba3-b79f-52a7-a20c-31ed52777f4e
DOI: 10.20944/preprints202603.2370.v1

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