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Multi-Omic Integration of Single-Cell, Spatial, and Bulk RNA-Seq Deciphers Endothelial Heterogeneity and WWTR1-Mediated Vascular Reprogramming in Keloids

2026-04-07

Abstract excerpt

<title>Abstract</title> <p>Keloids are complex fibroproliferative disorders characterized by persistent inflammation and vascular dysfunction. However, the high-resolution cellular landscape of their endothelial niche remains poorly defined due to the limited availability of specialized transcriptomic datasets. In this study, we addressed this critical knowledge gap by integrating single-cell RNA sequencing (scRN...

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Literature Corpus work: afedb587-613a-5f17-91aa-ab24e2c07737
DOI: 10.21203/rs.3.rs-9319391/v1

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