Article

Identification of a risk allele at SLC41A3 and a protective allele HLA-DPB1*02:01 associated with sarcopenia in Japanese

2024-10-16

Abstract excerpt

<title>Abstract</title> <p><bold>Background </bold>Age-related alterations in muscle tissue morphology and function, as well as chronic pro-inflammatory conditions, contribute to the development of sarcopenia. To elucidate the multidimensional pathogenesis of sarcopenia, we performed a comprehensive genetic analysis, including common variants, rare variants and human leukemia antigen (HLA). <bold>Methods </bold>A...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: af9fa503-29c9-5218-91ff-f0333b9789aa
DOI: 10.21203/rs.3.rs-4967742/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Identification of a risk allele at SLC41A3 and a protective allele HLA-DPB1*02:01 associated with sarcopenia in JapaneseDOI 10.21203/rs.3.rs-4967742/v1Read

Identification of a Risk Allele at SLC41A3 and a Protective Allele HLA-DPB1*02:01 Associated with Sarcopenia in Japanese.Semantic proximity Read

Genetic Associations with Aging Muscle: A Systematic Review.Semantic proximity Read

Disentangling the Genetics of Sarcopenia: prioritization of NUDT3 and KLF5 as genes for lean mass and HLA-DQB1-AS1 for hand grip strength based on associated SNPsSemantic proximity Read

Demographic and Genome Wide Association Analyses According to Muscle Mass Using Data of the Korean Genome and Epidemiology Study.Semantic proximity Read

Whole-exome sequencing and genome-wide association studies identify novel sarcopenia risk genes in Han Chinese.Semantic proximity Read

Identification of a shared, common haplotype cosegregating with an <i>SGCB</i> c.544A>C mutation in Indian patients affected with sarcoglycanopathySemantic proximity Read

Sarcopenia and Variation in the Human Leukocyte Antigen ComplexSemantic proximity Read

Analysis of ATP8B4 F436L Missense Variant in a Large Systemic Sclerosis CohortSemantic proximity Read

Relationship between DNA methylation changes and skeletal muscle massSemantic proximity Read

Disentangling the genetics of sarcopenia: prioritization of NUDT3 and KLF5 as genes for lean mass & HLA-DQB1-AS1 for hand grip strength with the associated enhancing SNPs & a scoring system.Semantic proximity Read

Epigenetic characterization of sarcopenia-associated genes based on machine learning and network screeningSemantic proximity Read

A novel caveolin-1 biomarker for clinical outcome of sarcopenia.Semantic proximity Read