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Article

Sarcopenia and Variation in the Human Leukocyte Antigen Complex

17 Feb 2019

Abstract excerpt

BACKGROUND: Aging is characterized by chronic inflammation plus loss of muscle mass and strength, termed sarcopenia. Human leukocyte antigen (HLA) types are drivers of autoimmune disease, although with limited penetrance. We tested whether autoimmune diagnoses are associated with sarcopenia, and whether HLA types and related genetic variants are associated with sarcopenia in autoimmune disease-free older people....

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PMID: 30772894
DOI: 10.1093/gerona/glz042

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