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ITGAM, MMP9 and THBS1 Define an Acute-Phase Extracellular Matrix-Immune Remodeling Module in Ischemic Stroke: An Integrated Multi-Cohort Transcriptomic Analysis Running title: ECM-immune module in acute ischemic stroke

2026-06-29

Abstract excerpt

<title>Abstract</title> <p>Background Acute ischemic stroke (IS) involves coordinated injury to the neurovascular unit, with extracellular matrix (ECM) remodeling and myeloid immune activation jointly driving blood-brain barrier (BBB) breakdown. Stable, functionally interpretable peripheral-blood molecular modules that capture this coupled ECM-immune process remain incompletely defined. We aimed to identify a tr...

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Literature Corpus work: af66f5c1-2126-5adf-989f-268e10298424
DOI: 10.21203/rs.3.rs-9835038/v1

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ITGAM, MMP9 and THBS1 Define an Acute-Phase Extracellular Matrix-Immune Remodeling Module in Ischemic Stroke: An Integrated Multi-Cohort Transcriptomic Analysis Running title: ECM-immune module in acute ischemic strokeDOI 10.21203/rs.3.rs-9835038/v1Read

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