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Article

Multi-omics Identifies Hub Genes and Immune Networks in Stroke-CAD Comorbidity

2026-08-07

Abstract excerpt

<title>Abstract</title> <p>Cerebral ischemic stroke (CIS) and coronary artery disease (CAD) frequently co-occur, yet their shared molecular basis remains unclear. Using multi-omics analysis of transcriptomic data, we identified 96 common differentially expressed genes enriched in immune-metabolic pathways. PPI network analysis prioritized hub genes (ARG1, CLEC7A, PECAM1, TRIB1), which showed consistent dysregulat...

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Literature Corpus work
de061ac8-3cb5-5fa1-b333-b6ab0f903dd8
DOI
10.21203/rs.3.rs-9361787/v1
Open publication

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Multi-omics Identifies Hub Genes and Immune Networks in Stroke-CAD ComorbidityDOI 10.21203/rs.3.rs-9361787/v1
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