Article

Spatial transcriptomics identifies novel <i>Pseudomonas aeruginosa</i> virulence factors

2024-06-20

Abstract excerpt

To holistically unravel the complexity of pathogen-host interactions within infected tissues we leverage a dual spatial transcriptomic approach that, for the first time, simultaneously captures the expression of Pseudomonas aeruginosa genes alongside the entire host transcriptome in a model of ocular infection. This innovative method reveals differential pathogen and host-specific gene expression patterns across...

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Literature Corpus work: ae8da24c-64b2-5c70-9697-088b60950069
DOI: 10.1101/2024.06.20.599896

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