Article

CD201+ fascia progenitors choreograph injury repair

2022-09-09

Abstract excerpt

<title>Abstract</title> <p>Optimal tissue recovery and organismal survival1 are achieved by tight spatiotemporal tuning of tissue inflammation, contraction and scar-formation. Here, we discover a multipotent fibroblast progenitor marked by CD201 expression in the fascia, the deepest connective tissue layer of the skin. Using murine skin injury models, single-cell transcriptomics, and genetic lineage tracing and a...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ae64bdc9-13b4-571a-9351-470956ebad98
DOI: 10.21203/rs.3.rs-2009916/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

CD201+ fascia progenitors choreograph injury repairDOI 10.21203/rs.3.rs-2009916/v1Read

CD201+ fascia progenitors choreograph injury repairSemantic proximity Read

4D multimodal wound healing atlas reveals organ-level controls of repair phase transitionsSemantic proximity Read

Spatiotemporal Single-Cell Roadmap of Human Skin Wound HealingSemantic proximity Read

Spatiotemporal single-cell roadmap of human skin wound healingSemantic proximity Read

Lef1 expression in fibroblasts maintains developmental potential in adult skin to regenerate woundsSemantic proximity Read

Longitudinal single cell transcriptomics reveals Krt8+ alveolar epithelial progenitors in lung regenerationSemantic proximity Read

Lef1 expression in fibroblasts maintains developmental potential in adult skin to regenerate woundsSemantic proximity Read

Charting the cellular biogeography in colitis reveals fibroblast trajectories and coordinated spatial remodelingSemantic proximity Read

Taxonomy of fibroblasts and progenitors in the synovial joint at single-cell resolutionSemantic proximity Read

Candidate rejuvenating factor GDF11 and tissue fibrosis: friend or foe?Semantic proximity Read

Molecular reframing of fibroblasts during resolution of arthritisSemantic proximity Read

Scar wars: mapping the fate of epithelial–mesenchymal–myofibroblast transitionSemantic proximity Read