Article

A genetically-defined population in the lateral and ventrolateral periaqueductal gray selectively promotes flight to safety

2022-01-21

Abstract excerpt

When encountering external threats, survival depends on the engagement of appropriate defensive reactions to minimize harm. There are major clinical implications for identifying the neural circuitry and activation patterns that produce such defensive reactions, as maladaptive overactivation of these circuits underlies pathological human anxiety and fear responses. A compelling body of work has linked activation of...

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Literature Corpus work: ae043ec5-ce78-5dc4-b8f1-cfeaa956ab31
DOI: 10.1101/2022.01.19.476981

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