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The generation of plasma cells and CD27 <sup>−</sup> IgD <sup>−</sup> B cells during Hantavirus infection are associated with distinct pathological findings

2019-08-02

Abstract excerpt

Human hantavirus infections can cause hemorrhagic fever with renal syndrome (HFRS), major signs of the disease being thrombocytopenia and transient kidney dysfunction. By a comprehensive and longitudinal study of circulating B cells, we demonstrate that these two pathologies associate with distinct effects on the humoral immune system during HFRS. Low thrombocyte counts strongly associated with an abnormal frequen...

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Literature Corpus work
add17a65-939e-5873-9c4d-8048b07ffd8f
DOI
10.1101/723585
Open publication

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The generation of plasma cells and CD27 <sup>−</sup> IgD <sup>−</sup> B cells during Hantavirus infection are associated with distinct pathological findingsDOI 10.1101/723585
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