Article

The Impact of CFTR Modulator Triple Therapy on Type 2 Inflammatory Response in Patients with Cystic Fibrosis

2023-05-10

Abstract excerpt

<title>Abstract</title> <p>Background Treatment of cystic fibrosis (CF) has been revolutionized by the use of cystic fibrosis transmembrane conductance regulator (CFTR) protein modulators such as elexacaftor/tezacaftor/ivacaftor (ETI) triple therapy. Prior studies support a role for type 2 (T2) inflammation in many people with CF (PwCF) and CF-asthma overlap syndrome (CFAOS) is considered a separate clinical ent...

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Literature Corpus work: ada45f94-a744-50e2-bccc-21886c8f206f
DOI: 10.21203/rs.3.rs-2846739/v1

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