Article

The Role of Triple CFTR Modulator Therapy in Reducing Systemic Inflammation in Cystic Fibrosis

2025-01-28

Abstract excerpt

<title>Abstract</title> <p><bold>Purpose: </bold>Cystic fibrosis (CF) is a genetic disease caused by mutations in the CFTR gene, leading to multisystemic complications, particularly in the lungs. CFTR dysfunction results in altered ion transport, chronic inflammation, and progressive lung damage. The triple therapy elexacaftor/tezacaftor/ivacaftor (ETI) has demonstrated significant improvements in pulmonary funct...

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Literature Corpus work: 224fc4f0-83c7-5a18-b0fd-566097fe1850
DOI: 10.21203/rs.3.rs-5874180/v1

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